Can Smoking Cause Mesothelioma?

Posted by and on May 16, 2019

The causal relationship between smoking and lung cancer is one of the strongest and most well established in all the health sciences. Asbestos defense attorneys have therefore been eager to determine if there is a causal relationship between smoking and mesothelioma. If such a relationship were identified, in certain cases with the right case-specific facts,
Read More

PFAS Inspired Litigation: An Increasing Number of Entities are at Risk

Posted by on May 8, 2019

Poly- and per-fluorinated alkyl substances (PFAS) are a group of synthesized chemicals that have been used for more than 50 years across many types of industries. For instance, PFAS compounds are widely used in non-stick products (e.g., Teflon), water- and/or stain-proof fabrics (e.g., clothing, furniture), food contact materials (e.g., certain types of cardboard), firefighting foams,
Read More

Signature Mutations Might be the Best Alternative Cause Defense You Never Heard Of

Posted by and on April 29, 2019

Genetic knowledge continues to increase at a rapid pace, transforming not only the practice of medicine but also toxic tort litigation. See our previous posts on this topic (e.g., here and here), our webinar, and our comprehensive white paper titled The Litigator’s Guide to Using Genomics in a Toxic Tort Case for more detailed information
Read More

New Study Identifies Potential Genetic Biomarker of Malignant Pleural Mesothelioma

Posted by on January 21, 2019

In a recently published article, Guarrera and colleagues report differential DNA methylation between malignant pleural mesothelioma (MPM) patients and cancer-free controls. These data represent some of the first evidence of detectable differences in DNA methylation in asbestos-exposed individuals with and without MPM. For asbestos defendants, these results provide support for the potential use of DNA
Read More

Wasting too much time searching for scientific articles and not enough time reading them?

Posted by on January 15, 2019

The volume of newly published scientific literature continues to grow at a staggering pace. A recent PubMed statistic indicates that the database hosts almost 29 million citations, with more than 1.3 million added in 2018 alone; a number that increased by 35% since 2013! And this accounts only for journals that are indexed by PubMed,
Read More

Malignant Mesothelioma in Women: Non-Occupational Asbestos Exposure or Genetics?

Posted by on January 9, 2019

A recent article by Marinaccio and colleagues examined gender differences and modalities of asbestos exposure in malignant mesothelioma (MM). The results are some of the first to examine gender differences in mesothelioma risk, with significantly more cases of MM attributed to occupational asbestos exposure in men than women. The author concluded that non-occupational exposure to
Read More

Malic Acid Under Fire in a Growing Number of Lawsuits and the Right Experts will be Key to Defending These Cases

Posted by on December 16, 2018

Malic acid is a versatile ingredient that is commonly found in food and dietary supplement products. Lately, malic acid has become the target of a growing number of lawsuits. Briefly, the suits allege that certain products are labeled as containing “no artificial flavors” but list malic acid as an ingredient. The suits continue by saying
Read More

Message to P/C Insurers: The Scientific Revolution is Here

Posted by on November 22, 2018

This article was co-written with William Wilt, President of Assured Research, a research and advisory firm dedicated to delivering highly customized, actionable research and analysis to insurance and investment professionals. It was adapted from their November 2018 briefing. In their February 2018 Assured Briefing warned: “Insurers need to get on board with the scientific revolution or risk being run
Read More

New Evidence Of Genetic Drivers For Mesothelioma In Persons With No Known Asbestos Exposure

Posted by on November 15, 2018

A recently published article authored by Drs. Michele Carbone, Haining Yang, and Harvey Pass (among others) is relevant to asbestos and talc defendants because it provides additional data supporting the conclusion that inherited genetic variations cause mesothelioma in some persons without any known exposure to asbestos. Most notably for asbestos and talc litigants, 57 out of the
Read More

New Paper Explores Heritable Genetic Factors Related To Mesothelioma

Posted by on October 11, 2018

A new paper by Kharazmi and colleagues present important data regarding the heritable nature of mesothelioma using epidemiological techniques to analyze the population-based Swedish Cancer Registry. The results, reported in the European Journal of Cancer, are important because the findings confirm that both genes and exposures are relevant, and on their face, appear helpful to
Read More